Synopsis: Brilliant but brusque surgeon Dr. Martin Best (Josh Charles) leaves his career in Boston to become the general practitioner in Port Wenn, a small fishing village in Maine where he spent summers as a child. Martin quickly alienates the quirky locals with his blunt bedside manner, while hiding a debilitating fear of blood that contributed to his departure from Boston. Although he would prefer to be left alone, Martin repeatedly finds himself drawn into the medical problems, personal conflicts and eccentricities of the town. (Courtesy FOX, 2026)
The Cast:
Josh Charles as Dr. Martin Best
Abigail Spencer as Louisa Gavin
Josh Segarra as Sheriff Mark Mylow
Cree as Elaine Denton
Annie Potts as Aunt Sarah
Stephen Spinella as Greg Garrison
Jason Veasey as George Brady
Carter Shimp as Al Large
Ben Lewis Doherty as Peter Cronk
Patch Darragh as Glendon Ross
Michael Potts as Gilbert Carlisle
Clea Lewis as Sally Mylow
Didi Conn as Geneva
John DiMaggio as Bert Large
Production Credits:
Best Medicine is based on the British television series Doc Martin, created by Dominic Minghella. The American adaptation was developed by Liz Tuccillo, who serves as showrunner and executive producer. Executive producers include Ben Silverman, Rodney Ferrell, Howard T. Owens, Tyson Bidner, Mark Crowdy, Philippa Braithwaite, Jay Karas and Liz Tuccillo. Jamie Babbit executive produced and directed the first two episodes. The series is produced by All3Media International, Propagate Content, Tuccillo, Inc. and Fox Entertainment Studios.
The Episodes:
Season One Episode Guide (FOX)
1-01 Docked--01/04/2026
Dr. Martin Best leaves his lucrative surgical career in Boston and moves to Port Wenn, Maine, to become the town's general practitioner. His blunt personality immediately puts him at odds with local teacher Louisa Gavin, while his first patients and a frightening encounter reveal his aversion to blood.
1-02 Bean There Done That--01/13/2026
Martin encounters his childhood bully and diagnoses a potentially contagious illness, forcing him to cancel Port Wenn's monthly bean supper and angering the townspeople. Meanwhile, Elaine attempts to help Martin, while Louisa notices Mark growing closer to her teaching assistant.
1-03 Take Me Out of the Ballgame--01/20/2026
Martin accidentally breaks the arm of Port Wenn's star high-school baseball player, who happens to be the son of his childhood bully. As the town turns against him, Elaine moves into Martin's waiting room after a dispute with her mother, while Louisa takes on a leadership role at the school.
1-04 All the World's Ablaze--01/27/2026
Martin becomes involved in another medical situation in Port Wenn while continuing to struggle with the consequences of his blood phobia and his increasingly complicated relationships with the townspeople.
1-05 Hello Darkness, My Port Wenn--02/03/2026
Martin faces another unusual medical case as his efforts to maintain a professional distance from Port Wenn's residents become increasingly difficult.
1-06 Eyewitness Blues--02/10/2026
Martin deals with a medical mystery while the close-knit community's personal relationships create additional complications for the reluctant doctor.
1-07 There Might Be Blood--02/17/2026
Martin's debilitating blood phobia becomes increasingly difficult to conceal as another medical emergency puts his abilities and his future in Port Wenn under pressure.
1-08 The Bogfather--02/24/2026
Martin is drawn into another unusual situation in Port Wenn as the town's eccentric residents create new problems for the doctor who would prefer to keep his distance.
1-09 Doc Martin--03/03/2026
Martin's medical expertise and his increasingly complicated relationship with Port Wenn's residents come into focus as he faces another challenging case.
1-10 Port Wenn-ings And A Funeral--03/10/2026
Martin treats a patient experiencing hallucinations while Aunt Sarah becomes angry over a disputed will. A medical emergency ultimately forces Martin to confront his fear of blood.
1-11 Mind Your Own Buboes--03/24/2026
Port Wenn goes into lockdown after a patient with fleas raises fears of plague. Meanwhile, gossip about Martin and Louisa spreads through town, while Aunt Sarah deals with a betrayal involving Greg and George.
1-12 A Tale of Two Sister Cities--03/31/2026
Martin becomes suspicious of Port Wenn's visiting Norwegian sister-city delegation. Louisa sees a specialist who happens to be Martin's former partner, while Greg, George and Sheriff Mark each face unexpected medical problems.
1-13 Norway No How--04/07/2026
The residents of Port Wenn discover the truth about their Norwegian sister-city arrangement. Martin confronts his blood phobia, delivers a baby and encounters his former partner, while Louisa receives important medical results. Meanwhile, Al and Elaine face an uncertain future.
Season Two Episode Guide (Fox)
2-01 Be Careful What You Fish For—09/22/2026
While Martin continues to struggle with his blood phobia, a mermaid washes ashore in Port Wenn to the amazement of everyone in town. Meanwhile, Judith, a well-meaning townsperson (guest star Andrea Martin), creates havoc while on prescribed oxygen, Louisa continues to see Martin’s girlfriend Eden for medical guidance and Greg and George’s success from the seas urchin boom take its toll on the both of them.
2-02 Breakin’ In Is Hard To Do—09/29/2026
When the Port Wenn pharmacy is robbed, including Louisa’s critical time-sensitive medicine, Martin deduces that the culprit desperately needs his help. Meanwhile, Greg and George clash with a rival food truck owner, Sarah tries to bond with Eden, and Martin is on the receiving end of a special brand of Port Wenn affection.
2-03 Crate Expectations—10/06/2026
As the citizens of Port Wenn get competitive during their annual floating crate race, Martin urgently tries to give important medical advice when three men have positive pregnancy tests. Meanwhile, Eden learns she wants to be liked after her singing ‘causes’ a man to pass out and former record-holder Sarah coaches Peter in the art of crate racing